The third generation of test tube baby technology is divided into: PGT-M embryo preimplantation genetic diagnosis, and PGT-A embryo preimplantation chromosome screening

PGT-M is preimplantation genetic diagnosis (also known as PGD). If a patient is at risk for a known genetic disorder or has another monogenic disorder, PGT-M can be used to exclude embryos with these genetic traits.

PGT-M are looking for known monogenic disorders on specific chromosomes. Indications: chromosomal abnormalities, monogenic disorders, hereditary disorders, HLA matching (stem cell transplantation for blood disorders), and couples who have had children.